Defeat McCain in November.

Eyes on the prize, people. John McCain in the White House will undo what vestiges of reproductive freedom there are left for women in this country.
Don't tell me that doesn't matter. He has stated repeatedly that he is in favor of repealing Roe V Wade.
To some people, the evidence of McCains utter corruption during the S and L scandals of the 80s, and his role as one of the Keating Five is "ancient history" but to me it is one of the reasons why the man should be disqualified from holding public office. He is a symbol of the corruption of big money capitalism at home and abroad.
ETA: Cliff Schecter's book The Real McCain: Why Conservatives Don't Trust Him--and Why Independents Shouldn't is a scrupulously documented record of McCain's actions and words.